A public-private partnership to improve botanical safety


The Botanical Safety Consortium (BSC) was officially convened in November 2019, as the result of a Memorandum of Understanding between the US Food and Drug Administration (FDA), the National Institutes of Health’s National Institute of Environmental Health Sciences (NIEHS), and the non-profit Health and Environmental Sciences Institute (HESI).

Our current charge is to evaluate the suitability of assays for botanicals as complex mixtures.

The BOTANICAL SAFETY CONSORTIUM will provide a sound scientific basis for integrating existing botanical safety & toxicity information with the latest toxicological tools. 

This multi-partite, multi-stakeholder international effort will bring together key scientific experts to enhance the botanical safety toolkit and bring clarity to botanical dietary ingredient assessments.

Society of Toxicology 2023 Meeting

19-23 March 2023 The HESI Botanical Safety Consortium will be attending SOT2023 in person in Nashville. You can connect at the following events below: Symposium:…

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Toxicology Forum 2023 Winter Meeting

23 January 2023 The HESI Botanical Safety Consortium will host an event titled “Advancement of Botanical Safety Using New Approach Methodologies” at the Toxicology Forum…

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BSC Webinar: An In-Silico Method To Predict Cardiotoxicity In Botanical Substances

29 November 2022 The HESI Botanical Safety Consortium will host a webinar on Tuesday November 29 at 11 am ET from Dr. Jeremy Billson (InoCardia)…

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Engage with a broad group of global stakeholders to leverage the best scientific approaches

Establish the appropriate levels of chemical characterization for complex botanical substances

Identify pragmatic, fit-for-purpose, in vitro & in silico assays to evaluate botanical safety

Evaluate the application of these tools via comparison to the currently available safety information

Integrate these tools and approaches into a framework that can facilitate robust evaluation of botanical substances

HESI is a non-profit, 501c3 charitable organization that convenes leading scientists from the public and private sector to identify emerging health challenges and solutions, translates science from research to application, and enhances the protection of human and the environment health worldwide.

For more information, please contact: botanicalsafety@hesiglobal.org.