New publication in Regulatory Toxicology and Pharmacology

Improving the rigor and utility of botanical toxicity studies: Recommended resources Deval Patel, Barbara C. Sorkin, Constance A. Mitchell, Michelle R. Embry, Sharline Rina-Kong, Rebecca E. Adams, Emily R. DeTemple, Aalekhya Reddam, Stefan Gafner, Olaf Kelber, Cynthia V. Rider, Hellen Oketch-Rabah, Amy L. Roe, Robin J. Marles, Joseph Dever, Steven Dentali. Regulatory Toxicology and Pharmacology. https://doi.org/10.1016/j.yrtph.2023.105471…

New BSC Review

Potential pharmacokinetic interactions with concurrent use of herbal medicines and a ritonavir-boosted COVID-19 protease inhibitor in low and middle-income countries Dallas J. Smith, Huichang Bi, Josias Hamman, Xiaochao Ma, Constance Mitchell, Kumbukani Nyirenda, Tsitsi Monera-Penduka, Hellen Oketch-Rabah, Mary F. Paine, Syril Pettit, Wihan Pheiffer, Richard B. Van Breemen and Michelle Embry. Frontiers in Pharmacology. https://doi.org/10.3389/fphar.2023.1210579 In…

BSC 2023 Annual Meeting

28 September 2023 Botanical Safety Consortium 2023 Annual Meeting held virtually on Thursday, September 28, 2023 from 9:00 – 3:30 (US Eastern). The meeting is free an open to all. Meeting flyer can be downloaded here.   Click to Register

SPS 2023 Annual Meeting

18 – 21 September 2023 HESI Botanical Safety Consortium Cardiotoxicty Technical Working Group poster at the 2023 Safety Pharmacology Society Annual Meeting in Brussels, Belgium.   P132: From neat compounds to complex mixtures: A potential screening strategy for cardiotoxic potential of botanicals. View full poster here. Go to Meeting Website

ETS 2023 Annual Meeting

17 – 20 September 2023 HESI Botanical Safety Consortium DART Technical Working Group poster at the 51st Annual Meeting of the European Teratology Society in Madrid, Spain. Go to Meeting Website

EMGS 2023 Annual Meeting

9 – 13 September 2023 HESI Botanical Safety Consortium Genotoxicity Technical Working Group poster presentation entitled “A Strategy for Developing a Robust Framework of Genotoxicity Assays for Safety Assessment of Botanicals” at the Environmental Mutagenesis & Genomics Society 54th Annual Meeting in Chicago, IL, USA. Go to Meeting Website

ASP2023 – Current Topics in Botanical Safety Workshop

22 July 2023, 1:30 – 4:30pm HESI Botanical Safety Consortium workshop on Saturday, 22 July from 1:30 – 4:30pm at the 2023 American Society of Pharmacognosy Annual Meeting in Rockville, Maryland. Current Topics in Botanical Safety Sponsored by:  The Botanical Safety Consortium Chairs:  Dr. Hellen O’Ketch-Rabah & Dr. Michelle Embry The growing popularity and interest…

71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)

July 5, 2023 BSC sponsored session on “Current Topics in Botanical Safety” at the 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in Dublin, Ireland. View full program HERE

ICSB 2023

25 April 2023 HESI Botanical Safety Consortium session at the 21st International Conference on the Science of Botanicals (ICSB). ICSB Session 7a: Botanical Safety Assessment: Updates From The BSC Chair: Dan Marsman, Proctor & Gamble Location: OCC Auditorium Date:25 April 2023 at 1 pm-2:15 pm CT 1:00-1:25 Connie Mitchell, Health And Environmental Sciences Institute (HESI) – The…

Society of Toxicology 2023 Meeting

19-23 March 2023 HESI Botanical Safety Consortium at SOT2023 in person in Nashville. Symposium: New Approach Methodologies to Evaluate Botanical Safety, Monday 20 March, 1:45 pm – 4:30 pm Poster: Predicted Pharmacokinetic Properties of Botanical Constituents, Tuesday 21 March, 2:30 – 4:15 am Poster: A Potential Screening Strategy for Neuroactive Potential of Botanicals, Wednesday 22…

New publication in Regulatory Toxicology and Pharmacology

Improving the rigor and utility of botanical toxicity studies: Recommended resources Deval Patel, Barbara C. Sorkin, Constance A. Mitchell, Michelle R. Embry, Sharline Rina-Kong, Rebecca E. Adams, Emily R. DeTemple, Aalekhya Reddam, Stefan Gafner, Olaf Kelber, Cynthia V. Rider, Hellen Oketch-Rabah, Amy L. Roe, Robin J. Marles, Joseph Dever, Steven Dentali. Regulatory Toxicology and Pharmacology. https://doi.org/10.1016/j.yrtph.2023.105471…

New BSC Review

Potential pharmacokinetic interactions with concurrent use of herbal medicines and a ritonavir-boosted COVID-19 protease inhibitor in low and middle-income countries Dallas J. Smith, Huichang Bi, Josias Hamman, Xiaochao Ma, Constance Mitchell, Kumbukani Nyirenda, Tsitsi Monera-Penduka, Hellen Oketch-Rabah, Mary F. Paine, Syril Pettit, Wihan Pheiffer, Richard B. Van Breemen and Michelle Embry. Frontiers in Pharmacology. https://doi.org/10.3389/fphar.2023.1210579 In…

BSC 2023 Annual Meeting

28 September 2023 Botanical Safety Consortium 2023 Annual Meeting held virtually on Thursday, September 28, 2023 from 9:00 – 3:30 (US Eastern). The meeting is free an open to all. Meeting flyer can be downloaded here.   Click to Register

SPS 2023 Annual Meeting

18 – 21 September 2023 HESI Botanical Safety Consortium Cardiotoxicty Technical Working Group poster at the 2023 Safety Pharmacology Society Annual Meeting in Brussels, Belgium.   P132: From neat compounds to complex mixtures: A potential screening strategy for cardiotoxic potential of botanicals. View full poster here. Go to Meeting Website

ETS 2023 Annual Meeting

17 – 20 September 2023 HESI Botanical Safety Consortium DART Technical Working Group poster at the 51st Annual Meeting of the European Teratology Society in Madrid, Spain. Go to Meeting Website

EMGS 2023 Annual Meeting

9 – 13 September 2023 HESI Botanical Safety Consortium Genotoxicity Technical Working Group poster presentation entitled “A Strategy for Developing a Robust Framework of Genotoxicity Assays for Safety Assessment of Botanicals” at the Environmental Mutagenesis & Genomics Society 54th Annual Meeting in Chicago, IL, USA. Go to Meeting Website

ASP2023 – Current Topics in Botanical Safety Workshop

22 July 2023, 1:30 – 4:30pm HESI Botanical Safety Consortium workshop on Saturday, 22 July from 1:30 – 4:30pm at the 2023 American Society of Pharmacognosy Annual Meeting in Rockville, Maryland. Current Topics in Botanical Safety Sponsored by:  The Botanical Safety Consortium Chairs:  Dr. Hellen O’Ketch-Rabah & Dr. Michelle Embry The growing popularity and interest…

71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)

July 5, 2023 BSC sponsored session on “Current Topics in Botanical Safety” at the 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in Dublin, Ireland. View full program HERE

ICSB 2023

25 April 2023 HESI Botanical Safety Consortium session at the 21st International Conference on the Science of Botanicals (ICSB). ICSB Session 7a: Botanical Safety Assessment: Updates From The BSC Chair: Dan Marsman, Proctor & Gamble Location: OCC Auditorium Date:25 April 2023 at 1 pm-2:15 pm CT 1:00-1:25 Connie Mitchell, Health And Environmental Sciences Institute (HESI) – The…

Society of Toxicology 2023 Meeting

19-23 March 2023 HESI Botanical Safety Consortium at SOT2023 in person in Nashville. Symposium: New Approach Methodologies to Evaluate Botanical Safety, Monday 20 March, 1:45 pm – 4:30 pm Poster: Predicted Pharmacokinetic Properties of Botanical Constituents, Tuesday 21 March, 2:30 – 4:15 am Poster: A Potential Screening Strategy for Neuroactive Potential of Botanicals, Wednesday 22…

BOTANICAL SAFETY CONSORTIUM

A public-private partnership to improve botanical safety

The Botanical Safety Consortium (BSC) was officially convened in November 2019, as the result of a Memorandum of Understanding between the US Food and Drug Administration (FDA), the National Institutes of Health’s National Institute of Environmental Health Sciences (NIEHS), and the non-profit Health and Environmental Sciences Institute (HESI).

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Our current charge is to evaluate the suitability of assays for botanicals as complex mixtures.

Latest News

Toxicology Forum 2023 Winter Meeting

23 January 2023 HESI Botanical Safety Consortium event titled “Advancement of Botanical Safety Using New Approach Methodologies” at the Toxicology Forum 2023 Winter Meeting on January 23, 2023…

BSC Webinar: An In-Silico Method To Predict Cardiotoxicity In Botanical Substances

29 November 2022 The HESI Botanical Safety Consortium will host a webinar on Tuesday November 29 at 11 am ET from Dr. Jeremy Billson (InoCardia) entitled “An In-Silico…

BSC at the 33rd German Society for Environmental Mutation Research Meeting (GUM)

6 October 2022 The Botanical Safety Consortium is hosting a session at the 33rd German Society for Environmental Mutation Research Meeting (GUM). When: October 6th, 2022 4:15 – 5:45pm…

BSC Annual Meeting

27 September 2022 Due to continued uncertainties with COVID-19, feedback from our stakeholders and the goals of the meeting, we have decided to make this year’s Botanical Safety…

BSC at ICT2022

18 – 21 September 2022 International Congress of Toxicology in Maastricht, the Netherlands 18 September to 21 September “New Approach Methodologies to Evaluate Botanical Safety” – poster by Dr. Michelle Embry,…

BSC at the 70th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA)

August 28-31, 2022 The BSC is planning a workshop during the 70th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA),…

BSC at the International Conference on Environmental Mutagens, Ottawa

27 August – 1 September 2022 International Conference on Environmental Mutagens in Ottawa, Canada 27 August to 1 September 2022 – “A Strategy for Developing a Framework of Genotoxicity Assays for…

BSC at ICSB 2022

March 28-31st, 2022 The Botanical Safety Consortium will have a session at the International Conference on the Science of Botanicals (ICSB 2022) entitled “Botanical Safety Assessment: Updates from…

BSC at SOT 2022

March 27-31st, 2022 The Botanical Safety Consortium presented at the 2022 Society of Toxicology meeting, which was held virtually and in person in San Diego, CA March 27-31,…

Botanical Safety Consortium Stakeholder Council Webinar Series February 22, 2022 @ 11am EST

Chemical Safety of Phytomedicines – Perspectives for in vitro testing strategies? The Botanical Safety Consortium hosted an open webinar on Tuesday 22 February 11 am -12 pm ET.…

The BOTANICAL SAFETY CONSORTIUM will provide a sound scientific basis for integrating existing botanical safety & toxicity information with the latest toxicological tools. 

This multi-partite, multi-stakeholder international effort will bring together key scientific experts to enhance the botanical safety toolkit and bring clarity to botanical dietary ingredient assessments.

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