Botanical Safety Consortium News
Updates, publications, and announcements from the BSC community.
American Society of Cellular and Computational Toxicology 14th Annual Meeting
22 October 2025 The Botanical Safety Consortium (BSC) is proud to participate in the 2025 Annual Meeting of the American Society for Cellular and Computational Toxicology (ASCCT)-a leading forum for…
Safety Pharmacology Society 2025 Annual Meeting
13 – 15 October 2025 The HESI Botanical Safety Consortium is presenting a poster at the Safety Pharmacology Society 2025 Annual Meeting from 13 – 15 October 2025, in Utrecht,…
2025 Society for Birth Defects Research and Prevention Annual Meeting
28 June – 2 July 2025 The Botanical Safety Consortium will be presenting a poster at the 2025 Society for Birth Defects Research and Prevention Annual Meeting in Denver, Colorado. Date: Monday, June…
New publication: Integration of computational models to predict botanical phytochemical constituent clearance routes by the extended clearance classification system (ECCS)
Integration of computational models to predict botanical phytochemical constituent clearance routes by the extended clearance classification system (ECCS) Liu et al., 2025. Toxicology and Applied Pharmacology. https://doi.org/10.1016/j.taap.2025.117385 The Botanical Safety…
New publication: Developing a Screening Strategy to Identify Hepatotoxicity and Drug Interaction Potential of Botanicals
Developing a Screening Strategy to Identify Hepatotoxicity and Drug Interaction Potential of Botanicals. Roe et al., 2024. Journal of Dietary Supplements. https://doi.org/10.1080/19390211.2024.2417679 The HESI Botanical Safety Consortium‘s Hepatotoxicity Working Group has developed…
New publication: Botanical-induced toxicity: Liver injury and botanical-drug interactions. A report on a Society of Toxicology Annual Meeting symposium
Koturbash et al., 2024. Botanical-induced toxicity: Liver injury and botanical-drug interactions. A report on a Society of Toxicology Annual Meeting symposium. Regulatory Toxicology and Pharmacology. https://doi.org/10.1016/j.yrtph.2024.105708 This article addresses the growing public…
New publication: Chemical Standardization of Milk Thistle (Silybum marianum L.) Extract Using UHPLC-MS/MS and the Method of Standard Addition
A new paper from the HESI Botanical Safety Consortium describes the development and validation of a novel method for quantifying the constituents in milk thistle extracts to ensure consistency and reliability in…
New publication: Screening tools to evaluate the neurotoxic potential of botanicals: building a strategy to assess safety
A recent article from the Botanical Safety Consortium (BSC) Neurotoxicity Working Group aims to evaluate existing NAMs for neurotoxicity screening of botanicals as complex mixtures. The article provides background on three assays or…
New publication: Prediction of physicochemical and pharmacokinetic properties of botanical constituents by computational models
A newly published study from the Botanical Safety Consortium, selected for the cover of Journal of Applied Toxicology, used computational models to predict the physiochemical and pharmacokinetic properties of botanical constituents. …
New publication: Within-laboratory reproducibility of Ames test results: Are repeat tests necessary?
A cross-sector group of experts from the Health and Environmental Sciences Institutes (HESI)’s Botanical Safety Consortium (BSC) and Genetic Toxicology Technical Committee (GTTC) analyzed data from the National Toxicology Program (NTP) Ames test database…