New publication in Food and Chemical Toxicology

Neuroactivity screening of botanical extracts using microelectrode array (MEA) recordings Regina G.D.M. van Kleef, Michelle R. Embry, Constance A. Mitchell, Remco H.S. Westerink. Food and Chemical Toxicology. https://doi.org/10.1016/j.fct.2024.114438 The HESI Botanical Safety Consortium collaborates to develop screening strategies that can efficiently identify botanical-induced toxicity. The study presented here evaluates the applicability of in vitro multi-well microelectrode…

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International Congress on Natural Products Research (ICNPR)

13 – 17 July 2024 The Botanical Safety Consortium is holding a training course as part of the meeting on Saturday 13 July entitled “Cultivating Safety: Toxicology 101 of Botanicals and Natural Products.“ This course will offer a deep dive into the world of botanicals, bridging the gap between their traditional uses and modern applications in supplements,…

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ICSB 2024

15 -18 April 2024 The Botanical Safety Consortium will be in attendance and presenting at the 22nd International Conference on the Science of Botanicals. Speakers include Connie Mitchell (HESI), and committee members Cynthia Rider (NIEHS), Amy Roe (P&G), Bill Gurley (U of Mississippi), and Holly Johnson (AHPA).

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34th German Society for Environmental Mutation Research Meeting (GUM)

20 – 22 March 2024 The Botanical Safety Consortium will present two posters at the 34th German Society for Environmental Mutation Research Meeting (GUM). When: 20 – 22 March, 2024 Where: Kaiserslautern, Germany A Strategy for Developing a Robust Framework of Genotoxicity Assays for Safety Assessment of Botanicals The Botanical Safety Consortium: Collaborative Effort to…

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SOT 2024

10 – 14 March 2024 The BSC will be presenting at SOT 2024 in Salt Lake City, UT, USA. Monday, March 11@1:45-4:30pm Symposium Session: Botanical-Induced Toxicity: Liver Injury and Botanical Drug Interactions, chaired by Amy Roe (P&G). BSC speakers include Steve Ferguson (NIEHS), Philip Yeager (US FDA), Mary Paine (Washington State University), Igor Koturbash (university Arkansas…

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Botanical Safety Consortium: Introduction and Updates

18 January 2024 Connie Mitchell, Michelle Embry & Julie Krzykwa will be presenting to the US FDA Center for Food Safety and Applied Nutrition (CFSAN) to update the progress of the HESI Botanical Safety Consortium.

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New publication in Regulatory Toxicology and Pharmacology

Improving the rigor and utility of botanical toxicity studies: Recommended resources Deval Patel, Barbara C. Sorkin, Constance A. Mitchell, Michelle R. Embry, Sharline Rina-Kong, Rebecca E. Adams, Emily R. DeTemple, Aalekhya Reddam, Stefan Gafner, Olaf Kelber, Cynthia V. Rider, Hellen Oketch-Rabah, Amy L. Roe, Robin J. Marles, Joseph Dever, Steven Dentali. Regulatory Toxicology and Pharmacology. https://doi.org/10.1016/j.yrtph.2023.105471…

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New BSC Review

Potential pharmacokinetic interactions with concurrent use of herbal medicines and a ritonavir-boosted COVID-19 protease inhibitor in low and middle-income countries Dallas J. Smith, Huichang Bi, Josias Hamman, Xiaochao Ma, Constance Mitchell, Kumbukani Nyirenda, Tsitsi Monera-Penduka, Hellen Oketch-Rabah, Mary F. Paine, Syril Pettit, Wihan Pheiffer, Richard B. Van Breemen and Michelle Embry. Frontiers in Pharmacology. https://doi.org/10.3389/fphar.2023.1210579 In…

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BSC 2023 Annual Meeting

28 September 2023 Botanical Safety Consortium 2023 Annual Meeting held virtually on Thursday, September 28, 2023 from 9:00 – 3:30 (US Eastern). The meeting is free an open to all. Meeting flyer can be downloaded here.   Videos Welcome & Meeting Objectives: Ms. Connie Mitchell, HESI Botanical Safety Consortium Introduction and Updates: Dr. Cynthia Rider,…

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SPS 2023 Annual Meeting

18 – 21 September 2023 HESI Botanical Safety Consortium Cardiotoxicty Technical Working Group poster at the 2023 Safety Pharmacology Society Annual Meeting in Brussels, Belgium.   P132: From neat compounds to complex mixtures: A potential screening strategy for cardiotoxic potential of botanicals. View full poster here. Go to Meeting Website

Read More

New publication in Food and Chemical Toxicology

Neuroactivity screening of botanical extracts using microelectrode array (MEA) recordings Regina G.D.M. van Kleef, Michelle R. Embry, Constance A. Mitchell, Remco H.S. Westerink. Food and Chemical Toxicology. https://doi.org/10.1016/j.fct.2024.114438 The HESI Botanical Safety Consortium collaborates to develop screening strategies that can efficiently identify botanical-induced toxicity. The study presented here evaluates the applicability of in vitro multi-well microelectrode…

Read More

International Congress on Natural Products Research (ICNPR)

13 – 17 July 2024 The Botanical Safety Consortium is holding a training course as part of the meeting on Saturday 13 July entitled “Cultivating Safety: Toxicology 101 of Botanicals and Natural Products.“ This course will offer a deep dive into the world of botanicals, bridging the gap between their traditional uses and modern applications in supplements,…

Read More

ICSB 2024

15 -18 April 2024 The Botanical Safety Consortium will be in attendance and presenting at the 22nd International Conference on the Science of Botanicals. Speakers include Connie Mitchell (HESI), and committee members Cynthia Rider (NIEHS), Amy Roe (P&G), Bill Gurley (U of Mississippi), and Holly Johnson (AHPA).

Read More

34th German Society for Environmental Mutation Research Meeting (GUM)

20 – 22 March 2024 The Botanical Safety Consortium will present two posters at the 34th German Society for Environmental Mutation Research Meeting (GUM). When: 20 – 22 March, 2024 Where: Kaiserslautern, Germany A Strategy for Developing a Robust Framework of Genotoxicity Assays for Safety Assessment of Botanicals The Botanical Safety Consortium: Collaborative Effort to…

Read More

SOT 2024

10 – 14 March 2024 The BSC will be presenting at SOT 2024 in Salt Lake City, UT, USA. Monday, March 11@1:45-4:30pm Symposium Session: Botanical-Induced Toxicity: Liver Injury and Botanical Drug Interactions, chaired by Amy Roe (P&G). BSC speakers include Steve Ferguson (NIEHS), Philip Yeager (US FDA), Mary Paine (Washington State University), Igor Koturbash (university Arkansas…

Read More

Botanical Safety Consortium: Introduction and Updates

18 January 2024 Connie Mitchell, Michelle Embry & Julie Krzykwa will be presenting to the US FDA Center for Food Safety and Applied Nutrition (CFSAN) to update the progress of the HESI Botanical Safety Consortium.

Read More

New publication in Regulatory Toxicology and Pharmacology

Improving the rigor and utility of botanical toxicity studies: Recommended resources Deval Patel, Barbara C. Sorkin, Constance A. Mitchell, Michelle R. Embry, Sharline Rina-Kong, Rebecca E. Adams, Emily R. DeTemple, Aalekhya Reddam, Stefan Gafner, Olaf Kelber, Cynthia V. Rider, Hellen Oketch-Rabah, Amy L. Roe, Robin J. Marles, Joseph Dever, Steven Dentali. Regulatory Toxicology and Pharmacology. https://doi.org/10.1016/j.yrtph.2023.105471…

Read More

New BSC Review

Potential pharmacokinetic interactions with concurrent use of herbal medicines and a ritonavir-boosted COVID-19 protease inhibitor in low and middle-income countries Dallas J. Smith, Huichang Bi, Josias Hamman, Xiaochao Ma, Constance Mitchell, Kumbukani Nyirenda, Tsitsi Monera-Penduka, Hellen Oketch-Rabah, Mary F. Paine, Syril Pettit, Wihan Pheiffer, Richard B. Van Breemen and Michelle Embry. Frontiers in Pharmacology. https://doi.org/10.3389/fphar.2023.1210579 In…

Read More

BSC 2023 Annual Meeting

28 September 2023 Botanical Safety Consortium 2023 Annual Meeting held virtually on Thursday, September 28, 2023 from 9:00 – 3:30 (US Eastern). The meeting is free an open to all. Meeting flyer can be downloaded here.   Videos Welcome & Meeting Objectives: Ms. Connie Mitchell, HESI Botanical Safety Consortium Introduction and Updates: Dr. Cynthia Rider,…

Read More

SPS 2023 Annual Meeting

18 – 21 September 2023 HESI Botanical Safety Consortium Cardiotoxicty Technical Working Group poster at the 2023 Safety Pharmacology Society Annual Meeting in Brussels, Belgium.   P132: From neat compounds to complex mixtures: A potential screening strategy for cardiotoxic potential of botanicals. View full poster here. Go to Meeting Website

Read More