New publication: Advancing botanical safety
Advancing botanical safety: A strategy for selecting, sourcing, and characterizing botanicals for developing toxicological tools.
Waidyanatha et al., February 2024. Food and Chemical Toxicology. https://doi.org/10.1016/j.fct.2024.114537
Increases in botanical use, encompassing herbal medicines and dietary supplements, have underlined a critical need for an advancement in safety assessment methodologies. This manuscript highlights: 1) Botanical Safety Consortium's strategy for botanical selection, sourcing, and preparation of extracts to be used in in vitro assays, and 2) the approach utilized to characterize botanical extracts, using green tea and Asian ginseng as examples, to build confidence for use in biological assays.
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Fig. 1. Objectives of the Botanical Safety Consortium's Chemical Analysis Working Group; compile literature, identify methods and approaches, select botanicals, and maintain a library of botanicals.