New Publication: Chemical standardization of kava (Piper methysticum) extract using UHPLC-MS/MS and the method of standard addition
Measuring what is in a botanical extract is an essential step in studying its safety. A new publication from researchers working with HESI Global’s Botanical Safety Consortium examines how to measure key compounds in kava extract. The team at Oregon State University found that other components of the extract could suppress or enhance measurement signals,…
3rd International Congress of the African Phytomedicine Scientific Society
25 – 29 October 2026 Durban, South Africa Poster Title: “The Botanical Safety Consortium: A collaborative effort to advance the use of NAMs for evaluate natural product toxicity” Presenter: Angela Calderon, Auburn University Go to Event Page
New publication: A proposed evaluation of new approach methodologies for dermal toxicity assessment of botanicals
Botanicals are widely used in cosmetics and personal care products, but their complex and variable composition can make traditional safety assessment challenging. The HESI Global Botanical Safety Consortium has published a review proposing a strategy to evaluate new approach methodologies (NAMs) for assessing the dermal safety of botanicals. In this review, the authors: Examine NAMs…
BSC Launches ADME and Transcriptomics Working Groups
Help shape the next phase of botanical safety research The Botanical Safety Consortium (BSC) is exploring interest in forming two new Working Groups: 𝐀𝐃𝐌𝐄 𝐚𝐧𝐝 𝐆𝐮𝐭 𝐌𝐨𝐝𝐞𝐥𝐬 This group would look at the application of ADME tools for botanicals in light of newly available in vitro toxicity data. A focused effort will also explore gut…
Student Contributions Advance Botanical Safety Consortium Research
The Botanical Safety Consortium recognizes the contributions of Ms. Amani Abu Qanan and Mr. Jamie Lindsay, two students who supported the consortium while completing their MS degrees in Toxicology at the University of Birmingham under the guidance of Dr. Scott Glabermann. Amani led a literature review focused on potential botanical drug interactions for patients undergoing cancer treatment attempting…
2026 EMGS Virtual Annual Meeting
12 – 14 October 2026 The Botanical Safety Consortium will be attending the Environmental Mutagenesis and Genomics Society (EMGS) 2026 Annual Meeting. Poster Title: Are the Ames and In Vitro Micronucleus Assays Sufficient for Reliable Genotoxicity Screening of Botanical Extracts? Presenter: Stephanie Smith-Roe (NIEHS) Go to Event Page
Botanical Safety Consortium Annual Meeting
28 – 29 September 2026 Please join us for our Annual Meeting to get updates on the Botanical Safety Consortium. Free and open to all. Register Here Download Flyer View the Recordings Day 1 · 8 recordings ↓Day 2 · 8 recordings ↓ Day 1 8 recordings Day 1 Welcome and Logistics…
European Teratology Society 54th Annual Meeting
20 – 23 September 2026 Basel, Switzerland Poster Title: The use of new approach methodologies (NAMs) to screen for developmental and reproductive toxicity in complex botanical mixtures Presenter: Matthew Burbank, L’Oreal Go to Event Page
25th International Congress of the International Society for Ethnopharmacology
14 – 17 September 2026 Foligno, Italy Angela Calderon of Auburn University will present The Botanical Safety Consortium: A Collaborative Effort to Advance the Use of NAMs for Evaluating Natural Product Toxicity. The poster will highlight the Botanical Safety Consortium’s collaborative work to advance New Approach Methodologies for assessing the safety of botanicals…
EUROTOX 2026
13 – 16 September 2026 **S19-02: An Update from the Botanical Safety Consortium** Session S19: *New Approach Methodologies for the Safety Assessment of Botanicals* Presenter: Catherine Mahony, P&G Go to Event Page
The Botanical Safety Consortium (BSC) was officially convened in November 2019, as the result of a Memorandum of Understanding between the US Food and Drug Administration (FDA), the National Institutes of Health’s National Institute of Environmental Health Sciences (NIEHS), and the non-profit Health and Environmental Sciences Institute (HESI).
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Our current charge is to evaluate the suitability of assays for botanicals as complex mixtures.
Latest News
New Publication: Chemical standardization of kava (Piper methysticum) extract using UHPLC-MS/MS and the method of standard addition
Measuring what is in a botanical extract is an essential step in studying its safety. A new publication from researchers working with HESI Global’s Botanical Safety Consortium examines…
3rd International Congress of the African Phytomedicine Scientific Society
25 – 29 October 2026 Durban, South Africa Poster Title: “The Botanical Safety Consortium: A collaborative effort to advance the use of NAMs for evaluate…
New publication: A proposed evaluation of new approach methodologies for dermal toxicity assessment of botanicals
Botanicals are widely used in cosmetics and personal care products, but their complex and variable composition can make traditional safety assessment challenging. The HESI Global Botanical Safety Consortium…
BSC Launches ADME and Transcriptomics Working Groups
Help shape the next phase of botanical safety research The Botanical Safety Consortium (BSC) is exploring interest in forming two new Working Groups: 𝐀𝐃𝐌𝐄 𝐚𝐧𝐝 𝐆𝐮𝐭 𝐌𝐨𝐝𝐞𝐥𝐬 This…
Student Contributions Advance Botanical Safety Consortium Research
The Botanical Safety Consortium recognizes the contributions of Ms. Amani Abu Qanan and Mr. Jamie Lindsay, two students who supported the consortium while completing their MS degrees in Toxicology at the…
2026 EMGS Virtual Annual Meeting
12 – 14 October 2026 The Botanical Safety Consortium will be attending the Environmental Mutagenesis and Genomics Society (EMGS) 2026 Annual Meeting. Poster Title: Are…
Botanical Safety Consortium Annual Meeting
28 – 29 September 2026 Please join us for our Annual Meeting to get updates on the Botanical Safety Consortium. Free and open to all.…
European Teratology Society 54th Annual Meeting
20 – 23 September 2026 Basel, Switzerland Poster Title: The use of new approach methodologies (NAMs) to screen for developmental and reproductive toxicity in complex botanical…
25th International Congress of the International Society for Ethnopharmacology
14 – 17 September 2026 Foligno, Italy Angela Calderon of Auburn University will present The Botanical Safety Consortium: A Collaborative Effort to Advance the Use of…
EUROTOX 2026
13 – 16 September 2026 **S19-02: An Update from the Botanical Safety Consortium** Session S19: *New Approach Methodologies for the Safety Assessment of Botanicals* Presenter:…
