Botanical Safety Consortium News

New publication: Prediction of physicochemical and pharmacokinetic properties of botanical constituents by computational models

A newly published study from the Botanical Safety Consortium used computational models to predict the physiochemical and pharmacokinetic properties of botanical constituents.  This study investigated 103 major compounds from 13 botanicals…

Read More

New publication: Within-laboratory reproducibility of Ames test results: Are repeat tests necessary?

A cross-sector group of experts from the Health and Environmental Sciences Institutes (HESI)’s Botanical Safety Consortium (BSC) and Genetic Toxicology Technical Committee (GTTC) analyzed data from the National Toxicology Program (NTP) Ames test database…

Read More

New publication: Advancing botanical safety

Advancing botanical safety: A strategy for selecting, sourcing, and characterizing botanicals for developing toxicological tools. Waidyanatha et al., February 2024. Food and Chemical Toxicology. https://doi.org/10.1016/j.fct.2024.114537 Increases in botanical use, encompassing herbal…

Read More

New publication in Food and Chemical Toxicology

Neuroactivity screening of botanical extracts using microelectrode array (MEA) recordings Regina G.D.M. van Kleef, Michelle R. Embry, Constance A. Mitchell, Remco H.S. Westerink. Food and Chemical Toxicology. https://doi.org/10.1016/j.fct.2024.114438 The HESI Botanical…

Read More

New publication in Regulatory Toxicology and Pharmacology

Improving the rigor and utility of botanical toxicity studies: Recommended resources Deval Patel, Barbara C. Sorkin, Constance A. Mitchell, Michelle R. Embry, Sharline Rina-Kong, Rebecca E. Adams, Emily R. DeTemple,…

Read More

New BSC Review

Potential pharmacokinetic interactions with concurrent use of herbal medicines and a ritonavir-boosted COVID-19 protease inhibitor in low and middle-income countries Dallas J. Smith, Huichang Bi, Josias Hamman, Xiaochao Ma, Constance…

Read More

BSC 2023 Annual Meeting

28 September 2023 Botanical Safety Consortium 2023 Annual Meeting held virtually on Thursday, September 28, 2023 from 9:00 – 3:30 (US Eastern). The meeting is free an open to all.…

Read More

ASP2023 – Current Topics in Botanical Safety Workshop

22 July 2023, 1:30 – 4:30pm HESI Botanical Safety Consortium workshop on Saturday, 22 July from 1:30 – 4:30pm at the 2023 American Society of Pharmacognosy Annual Meeting in Rockville,…

Read More

BSC Webinar: An In-Silico Method To Predict Cardiotoxicity In Botanical Substances

29 November 2022 The HESI Botanical Safety Consortium will host a webinar on Tuesday November 29 at 11 am ET from Dr. Jeremy Billson (InoCardia) entitled “An In-Silico Method To…

Read More

BSC Annual Meeting

27 September 2022 Due to continued uncertainties with COVID-19, feedback from our stakeholders and the goals of the meeting, we have decided to make this year’s Botanical Safety Consortium’s Annual…

Read More